Nonalcoholic steatohepatitis (NASH) is a type of liver disease characterized by inflammation and liver cell damage caused by a buildup of fat in the liver. It is considered a more severe form of nonalcoholic fatty liver disease (NAFLD) and is often associated with obesity, diabetes, and other metabolic disorders. NASH can progress to more serious conditions such as cirrhosis, liver failure, and liver cancer, making it a significant health concern. Research in this area focuses on understanding the underlying mechanisms of NASH, identifying risk factors, developing diagnostic tools, and investigating potential treatments. Current research efforts include studying the role of genetics, lifestyle factors, and gut microbiota in the development of NASH, as well as testing various drugs and therapies to target inflammation and fat accumulation in the liver. The goal of this research is to improve diagnosis, management, and outcomes for individuals with NASH.